Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Thus assuming that type D personalities lack social interest is not correct but the right thing is that they might be interested in people but afraid to approach them because they fear rejection.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Concerns about the vulnerability of some emerging economies and gyrations in financial markets over the past few days should not dent “cautious optimism” about the global economy this year, leading central bankers and officials said on Saturday.
The average salary of St Gallen’s alumni jumped to $102,000 three years after graduation compared with $90,000 last year.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
People who are skeptical about this argument just need look at smartphones and personal computers, which have served as the technological driving force of the past century.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Comic skit “Big City Small Life”(Wang Ning, Chang Yuan and Ailun)
Stephen Curry scored 37 points to lead the defending NBA champions to their 12th straight win to open the season, a hard-fought 115-110 victory over the Toronto Raptors on Tuesday night.
Trends and targets in antiviral phototherapy
Here are the top 5 share repurchases authorized so far this year, according to data collected by Birinyi.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
In 2008, Janah talked to a call center worker from Dharavi, India, the largest slum in South Asia, while working as a consultant. The worker said there were millions of unemployed villagers as talented as he was. "I thought, 'What if outsourcing could generate a few dollars for billions of people, rather than billions of dollars for a wealthy few'" Janah says. She went on to launch Samasource, a tech platform that connects impoverished women and youth with large corporations like Google, LinkedIn, and Microsoft to complete digital projects. To date, the non-profit has helped over 16,000 people rise above the poverty line and it recently launched SamaUSA, a domestic program for low-income students living in San Francisco.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
In the most significant change in methodology since this ranking was first published in 2005, the FT now collects information about alumni’s first jobs after graduation. These data are used in conjunction with information about their current jobs, three years later. This allows the FT to calculate their salary increase since graduation — a new ranking criterion — as well as their career progress (see methodology).
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
Framing the ’80s
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Zhang's piece is “so lush and so rich and so full and so complete,” Google Doodle team leader Ryan Germick told the Washington Post. “Every leaf seemed to have life in it.”
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
It is not unusual for the documented wealth of China’s richest people to surge suddenly — or even for previously unknown tycoons to burst into prominence — as stock exchange listings and other public investments thrust them into the spotlight.
Two terrifically entertaining, ensemble-driven, fact-based procedurals about appalling crimes and the institutions — the Roman Catholic Church and Wall Street banks — that allowed corruption to fester. In addition to mustering righteous anger, Mr. McCarthy and Mr. McKay, in very different ways, managed to infuse the routines of modern work (answering phones, typing on keyboards, scrutinizing spreadsheets) with suspense, emotion and moral gravity.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Likewise, if the 11 countries led by Japan left in the TPP manage to salvage a deal following the US exit that could provide some balance in the region.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
I want to be in your arms this New Year.我要在你的怀抱里度过今年的春节。
Influenza neuraminidase: A druggable target for natural products
Though Hand was British Petroleum's SVP of Global Brand, Marketing and Innovation, for several years, she's on a much more environmentally friendly mission today. Project Frog aims to revamp the construction industry with simple-to-build spaces (they takes days, rather than months to construct) that consume about 50% less energy than traditional buildings for sectors like education and healthcare. Hand's plan seems to be working: revenue is expected to more than double this year.
Summly的一个早期版本──Trimit，于2011年7月出现在了苹果app store“新品推荐”栏目中。正是在这里，它被极具影响力的硅谷《科技博客》(TechCrunch)所关注，并迅速引起了李嘉诚的投资集团的注意。当达洛伊西奥收到李嘉诚的维港投资(Horizons Ventures)发来的电子邮件时，他只有15岁，并且基本没让什么人知道他所做的事情。在那之前，他从未与科技领域内的任何人物见过面，而他在Trimit的登记信息中也只是粗略形容自己是“伦敦的一家科技公司”。仅靠这一信息，谁也不会想到这家公司的管理和技术团队──事实上，它的全部职员──竟然是住在郊区卧室里的一个连车都不能开的小孩。
2. 大卫·维勒莱斯(David Virelles)，《姆波克》(Mbókò)，ECM。才华横溢的年轻钢琴手大卫·维勒莱斯继续着对非洲-古巴文化与仪式的深入研究，带着有条不紊的酷意与精神上的开放性。罗曼·迪亚兹(Román Díaz)担任打击乐手，这张迷人的组曲有着既古典又现代的深刻内涵。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The report said families back home receive an average of $200 a month, which makes up 60 percent of the household income.Using the steady flow of remittances, families can buy food, get housing, go to school, access healthcare, improve sanitation, or even invest in a business and have some savings, the report said.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
The runner-up was Lucy Kay, with Bars and Melody in third place.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Will the Saudi Aramco public offering debut on an international market
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
One of the most discussed potential use cases of the block chain is as a decentralized Uber. Instead of using an app, customers could order a car and pay the driver directly, cutting out the middleman. (Sorry, Travis Kalanick.) The block chain can be utilized for everything from the storage of secure documents (that is, a decentralized Dropbox, too) to “watermarking,” in which a specific coin could contain, say, the deed to your house. “The block chain is going to spawn decades of innovation,” says Ryan Selkis, director of investments at the Digital Currency Group, created by former SecondMarket founder Barry Silbert. “It could lead to things like frictionless share issuance, title transfers, smart contracts. Collectively these things make up the backbone of the economy. If you wanted to create a decentralized Uber, Dropbox, Facebook, you could reinvent the Internet.”
Inhibition of SARS coronavirus helicase by bismuth complexes
Rare pictures have been released showing the ancient sex toys that once belonged to the Chinese royals and aristocrats.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
“It’s horrible,” he said. “Whenever I see someone with a gun, I take it away and report it to police.”
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Game of Thrones
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
'If global demand picks up in the developed world, and you combine that with the growth in the emerging economies, I think the market is going to get tight,' he said, which means those mighty peaks could return to the oil-price graph.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Many economists doubt the European Central Bank will increase the size of its 1.46tn asset-purchase programme in 2016 despite assurances by ECB chief Mario Draghi that additional monetary stimulus is still on the table.
But Huy Vo, a senior specialist in public relations at Hawaiian, said the short flights, which make up half the airline’s routes, aren’t all that easy to operate. “Our geographic location certainly does give us an advantage, as well as our short-haul routes, ” Vo said. “However, the short-haul routes are the hardest to keep punctual, because the hops are very short, with brief ground time between flights, so any delay is difficult to make up.
《失常》，导演查理·考夫曼(Charlie Kaufman)与杜克·约翰逊(Duke Johnson)。
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
The Peoria, Ill.-based maker of heavy equipment authorized $10 billion in stock repurchases in January and expected to buy back $1.7 billion of its shares in the first quarter this year to complete its previous $7.5 billion repurchase initiative. The ongoing buybacks are "a result of our record cash flow," said CEO Doug Oberhelman.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Whiteness, in this context, is more than just skin color. You could define it as membership in the “ethno-national majority,” but that’s a mouthful. What it really means is the privilege of not being defined as “other.”
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
But only 14,000 tourists took advantage of the visa-free stopover, according to the Beijing General Station of Exit and Entry Frontier Inspection, well short of the 20,000 target officials had previously predicted.
For over two decades I have been writing about the rise of Asia and the dynamic driving it. There is an extraordinary consensus among east Asian leaders that Asia needs to use this window of opportunity to focus on economic development and growth. War is the biggest obstacle to development. If Asians were truly stupid, they would engage in such wars and derail their enormous development promise. Most Asian leaders, barring North Korea, understand well the dangers of war. Hence, while there will be tensions and rivalries in the region, there will be no wars in the region, in 2014 or in 2015. As 2015 unfolds, I would like to encourage all western pundits to understand the underlying Asian dynamic on its own terms, and not on the basis of western preconceptions.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
But the 3D version of the mascot image failed to dodge bullets, as critical netizens sneered at this version: "Reminds me of green and red lights." "Lost all the flair of that ink painting" "What are those balls under its ears?" "It is so ugly that I just want to cry."
Nothing tops the insensitivity and stupendous lack of awareness as Lohan's insensitive post five months ago.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Justin Bieber was the big winner of the evening at the American Music Awards last night, taking home four accolades including Favorite Pop/Rock Male Artist, Fa
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
其他机构有宝钢集团(Shanghai Baosteel Group)旗下为钢材交易商提供融资的欧冶云商(Ouyeel)、中国第六大银行招商银行(China Merchants Bank)旗下专注财富管理领域的小企业e家(Small Entrepreneur)等。
The year before, Taiwanese anti-China protesters chose the sunflower as the symbol for their cause.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Third, McDermott provides some protection against the possibility of Andre Roberson departing as a free agent in the summer.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Musk said he expects to be producing cars at a 100,000-a-year rate by the end of 2015.
A reporter was turned away at the unit where Ross lived, with a woman politely stating from behind the closed front door that the child’s mother isn’t ready to speak publicly.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Still, there are bulls in the market.
The exchanges revealed there is little major difference between the two in term of their approach to security and foreign affairs. On Iran both vowed it will not be allowed to have nuclear weapons. Rommey said he would introduce more stringent sanctions; Obama said they were already as stringent as they could possibly be.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The remains of the monarch -- depicted by William Shakespeare as a monstrous hunchback and often viewed as one of English history's greatest villains -- will now be solemnly reburied in the local cathedral.
When he wasn't programming or doing schoolwork, D'Aloisio began to fill his spare time reading about natural language processing. He'd studied languages as diverse as Latin and Mandarin, and became fascinated by concepts like grammatical frameworks, morpheme parsing and the 1960s work of the linguist Richard Montague. 'He's my favorite,' D'Aloisio enthuses. 'He theorized that natural language could be described like a syntactical programming language.'
A modular microarray imaging system for highly specific COVID-19 antibody testing
No students or teachers drank the poisoned water, the report said.
The University of Pittsburgh team used stem cells made from skin to make MCPs, a special kind of cell that acts as a precursor to cardiovascular tissue. They then placed these cells on a 3-D scaffold designed to support a mouse heart. Within 20 days, the new heart began beating at 40 to 50 beats per minute.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
《小镇疑云》，BBC America，3月4日播出。大卫·田纳特(David Tennant)携第二季归来，在这部引人共鸣的英国推理剧中继续饰演亚力克·哈迪(Alec Hardy)探员（去年他在美国翻拍版的《小镇疑云》[Gracepoint]中饰演埃米特·卡弗探员）。这部剧将于周一在英国首映，制作人们已经开始谈起第二季的秘密情节了，编剧克里斯·齐布纳尔(Chris Chibnall)在接受英国杂志采访时说的话可能会让剧迷不爱听，“第二季不是讲罪案的。”奥莉薇娅·科尔曼(Olivia Colman)继续饰演艾丽·米勒(Ellie Miller)探员，夏洛特·兰普林(Charlotte Rampling)和玛丽安娜·琼-巴普迪斯特(Marianne Jean-Baptiste)也加入了演员阵容。
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
1. Jennifer Lawrence
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
The most sought-after job as of Tuesday remained a position offered by the China Employment Training Technical Instruction Center in Beijing, which had drawn 1,430 applicants, the institute said.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Despite the confusion, executive producer Ed Razek has commended the Chinese partners as “wonderful and enthusiastic hosts.”
But Mr Stevenson said “this might reflect that the US is being bolder than the EU in protecting domestic steel producers”.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
8. 斯特吉尔·辛普森(Sturgill Simpson)，《乡村音乐的大现代之声》(Matamodern Sound in Country Music)，High Top Mountain。一支极为聪敏的乐队做出复古的改革：乡村乐中曾经发生过这样的事。但在斯特吉尔·辛普森突破性的第二张专辑中，他把这一点变成了可适应环境的标志，就建立在他那动人而通透的男中音之上。
There are 15 Chinese brands in the top 100, one more than last year and a sharp rise on a decade ago, when China Mobile was the only Chinese brand.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
"This film was about survival, adaptation and the triumph of the human spirit and more importantly it was about trust.”
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Chinese Premier Li Keqiang said the economy performed better than forecast in 2017 and expects annual gross domestic product growth of around 6.9 per cent, according to state media.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
她曾为Glitzy Girl、Sally Miller和Purple Pixies等服装公司担任模特，也为《Teen Vogue》《Cosmopolitan》《Elle》和《Seventeen》等杂志拍摄照片。
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
After being named Esquire's "Sexiest Women Alive" in October and Details' "Most F*ckable Celebrity" last month, the gorgeous 29-year-old has now snagged another honor: FHM's "Sexiest Woman In The World 2013," beating 99 other ladies and countless more who didn't even make the list.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
2. “Inside Out” (Pete Docter)
Who can forget Prince Harry's unprecedented communique to the media a few months ago over the then speculation over his girlfriend Meghan Markle?
Length-scale dependence of protein hydration-shell density
Pink, LeBron James, Selena Gomez, Ian Somerhalder, Jay-Z and Beyonce, Ben Affleckalso made the list.
In a televised debate on Monday night, Mr Wilders called on the Netherlands to expel the Turkish ambassador.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
保障房倡导者们则担心，如果重新区划做得不认真，那么居民社区或将迅速士绅化。“看看威廉斯堡(Williamsburg)发生了什么吧，”城市正义中心(Urban Justice Center)的社区开发项目负责人哈维·艾普斯坦(Harvey Epstein)说，他指的是房价上涨，“我不明白，它怎么就不可能发生在东纽约、布朗克斯或者法拉盛呢。”
At least 10 students lost their chance to attend Harvard College after posting "obscene memes" to a private Facebook chat, the main Harvard student newspaper reported.
About this collection
In fact, academic research suggests that other economic and social transformations unfolding at the same time have led many people to anchor themselves more fully in their whiteness — even as whiteness itself has lost currency.